Winfried ELIS,Seth ETTENBERG,Andrew Paul GARNER,Christian Carsten Silvester KUNZ,Tobias SEITZ
申请号:
US13693339
公开号:
US20130273029A1
申请日:
2012.12.04
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to antibodies or fragments thereof that target an epitope of a HER3 receptor residing in domain 2 of the HER3 receptor to block both ligand-dependent and ligand-independent signal transduction and tumor growth and compositions and methods of use thereof.