Elis, Winfried,Ettenberg, Seth,Garner, Andrew Paul,Kunz, Christian Carsten Silvester,Seitz, Tobias
申请号:
AU2012349736
公开号:
AU2012349736A1
申请日:
2012.12.04
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to antibodies or fragments thereof that target an epitope of a HER3 receptor residing in domain 2 of the HER3 receptor to block both ligand-dependent and ligand-independent signal transduction and tumor growth; and compositions and methods of use thereof.