Tetsuya Uchida,Maiko Taneichi,Kiichi Kajino,Masanori Matsui,Hiroshi Oda
申请号：
US12400269
公开号：
US08282938B2
申请日:
2009.03.09
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides an avian influenza vaccine containing a peptide-bound liposome wherein； the peptide contains:(1) an amino acid sequence shown by any one of SEQ ID NO:1 to 9, or(2) an amino acid sequence shown by any one of SEQ ID NO:1 to 9wherein one or two amino acids are substituted,has a length of 9 to 11 amino acids, andis capable of inducing HLA-restricted cytotoxic T lymphocytes；wherein the liposome contains a phospholipid having an acyl group with 14 to 24 carbon atoms and one unsaturated bond or a hydrocarbon group with 14 to 24 carbon atoms and one unsaturated bond, and a liposome stabilizer； andwherein the peptide is bound to the surface of the liposome.
