RECOMBINANT AVIAN INFLUENZA VIRUS HAVING IMPROVED IMMUNOGENICITY AND VACCINE COMPOSITION COMPRISING THE SAME

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专利权人:

KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

发明人:

PARK, MAN SEONG,박만성,PARK, MAN SEONGKR

申请号：

KR1020160169687

公开号：

KR1018619330000B1

申请日:

2016.12.13

申请国别(地区):

KR

年份:

2018

代理人:

摘要：

According to one embodiment of the present invention, provided is a recombinant influenza virus comprising H7 hemagglutinin (HA) in which at least two amino acids are glycosylated. The amino acids may be asparagine, and the glycosylation may be N-linked glycosylation (NLG). According to the present invention, immunogenicity and proliferation capability are improved.본 발명의 일 실시예에 따르면, 2 이상의 아미노산이 당쇄화(glycosylation)된 H7 헤마글루티닌(HA, Hemmaglutinin)을 포함하는, 재조합 인플루엔자 바이러스가 제공된다.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/