Steven A. CASTLEBERRY,Mohiuddin A. QUADIR,Paula T. HAMMOND
申请号：
US15739487
公开号：
US20180185513A1
申请日:
2016.06.23
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed herein are conjugated polymers comprising a polymer and an all-trans retinoic acid (ATRA) prodrug covalently bound to the polymer by a hydrolysable linker L or a pharmaceutically acceptable salt thereof, and methods of using same to treat certain disorders. In an embodiment, the conjugated polymer comprises poly (vinyl alcohol) covalently bound to ATRA through an ester linkage.
