Aurelio Galli,Heinrich J.G. Matthies,Naji N. Abumrad,India A. Reddy,Charles Robb Flynn,Kevin Erreger
申请号：
US15218976
公开号：
US20170020894A1
申请日:
2016.07.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Compositions and methods for treating addiction in a subject are disclosed. In particular, compositions and methods for treating addiction to a dopaminergic psychostimulant are disclosed. In some embodiments, addiction is treated by agonizing bile acid receptors in the subject. For example, in some embodiments, the method comprises administering to the subject a therapeutically effective amount of a composition comprising a therapeutically effective amount of a bile acid receptor agonist. In some embodiments, the method comprises surgically diverting bile acids in the subject in a manner suitable to increase circulating bile acids in the subject.
