1. A method of increasing mitophagy in a cell, comprising bringing the cell into contact with a USP30.2 inhibitor. A method for increasing mitochondrial ubiquitination in a cell, comprising contacting the cell with a USP30.3 inhibitor. Method of increasing ubiquitination of at least one, at least two, at least three, at least four, at least five, at least six, at least seven, at least eight, at least nine, at least at least ten, at least eleven, at least twelve, at least thirteen or fourteen proteins selected from Tom20, MIRO, MUL1, ASNS, FKBP8, TOM70, MAT2B, PRDX3, IDE, VDAC1, VDAC2, VDAC3, IP05, PSD13 , UBP13 and PTH2 in a cell, comprising bringing the cell into contact with a USP30.4 inhibitor. The method of claim 3, wherein the method comprises increasing the ubiquitination of at least one, at least two, or three amino acids selected from K56, K61, and K69 Tom 20.5. The method of claim 3, wherein the method comprises increasing the ubiquitination of at least one, at least two, at least three, at least four, at least five, at least six, at least seven, or eight amino acids, selected from K153, K187, K330, K427, K512, K535, K567 and K572 MIRO. 6. The method of claim 3, wherein the method comprises increasing the ubiquitination of at least one, at least two, or three amino acids selected from K273, K299, and K52 MUL1.7. The method of claim 3, wherein the method comprises increasing the ubiquitination of at least one, at least two, at least three, at least four, at least five, at least six, at least seven, at least seven eight or nine amino acids selected from K147, K168, K176, K221, K244, K275, K478, K504 and K556 ASNS. 8. The method of claim 3, wherein the method comprises increasing the ubiquitination of at least one at least1. Способ увеличения митофагии в клетке, включающий приведение клетки в контакт с ингибитором USP30.2. Способ увеличения митохондриального убиквитинирования в клетке, включающий приведение клетки в контакт с ингибитором USP30.3. Способ увелич
