SITEONE THERAPEUTICS, INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
MULCAHY, JOHN,PAJOUHESH, HASSAN,SHIBUYA, GRANT MASAAKI,DELWIG, ANTON,MILJANICH, GEORGE (DECEASED),DU BOIS, JUSTIN
申请号：
CA3000708
公开号：
CA3000708A1
申请日:
2016.09.30
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R1, X1 and X3 are as described herein.
