SITEONE THERAPEUTICS, INC.;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人:
MULCAHY, JOHN,PAJOUHESH, HASSAN,BECKLEY, JACOB,SHIBUYA, GRANT MASAAKI,DU BOIS, JUSTIN,MILJANICH, GEORGE (DECEASED),DELWIG, ANTON
申请号：
CA3058214
公开号：
CA3058214A1
申请日:
2018.03.29
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein.
