Siteone Therapeutics, Inc.;The Board of Trustees of the Leland Stanford Junior University
发明人:
申请号：
EP18720448.2
公开号：
EP3601291A1
申请日:
2018.03.29
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein.
