ANTIDOTE THERAPEUTICS, INC.;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人:
KALNIK, MATTHEW W.,THISTED, THOMAS,STONE, EVERETT,REED, CHARLES C.,RODNICK-SMITH, MAX
申请号：
CA3052928
公开号：
CA3052928A1
申请日:
2018.02.02
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Described are nicotine-degrading enzyme variants that exhibit increased nicotine-degrading activity and/or decreased immunogenicity relative to the wild-type NicA2 and NOX enzymes, compositions comprising the variants, and methods using them.
