USE OF LYSIN TO RESTORE/AUGMENT ANTIBACTERIAL ACTIVITY IN THE PRESENCE OF PULMONARY SURFACTANT OF ANTIBIOTICS INHIBITED THEREBY

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专利权人:

Contrafect Corporation

发明人:

WITTEKIND, Michael,SCHUCH, Raymond

申请号：

EP16781597

公开号：

EP3349781A2

申请日:

2016.09.16

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present disclosure provides methods and compositions useful for the prophylactic and therapeutic amelioration and treatment of infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa. The disclosure further provides compositions and methods of incorporating and utilizing lysin polypeptides of the present disclosure for augmenting the efficacy of antibiotics generally suitable for the treatment of Gram-negative bacterial infection.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/