SCHUCH, Raymond,HOFFENBERG, Simon,WITTEKIND, Michael
申请号:
EP16778940
公开号:
EP3349780A2
申请日:
2016.09.16
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present disclosure provides methods and compositions useful for the prophylactic and therapeutic amelioration and treatment of infections caused by Gram-negative bacteria, including Pseudomonas aeruginosa. The disclosure further provides compositions and methods of incorporating and utilizing lysin polypeptides of the present disclosure for augmenting the efficacy of antibiotics generally suitable for the treatment of Gram-negative bacterial infection.