Bramson, Jonathan,Helsen, Christopher W.,Denisova, Galina,Giri, Rajanish,Mwawasi, Kenneth Anthony
申请号：
AU2018202294
公开号：
AU2018202294A1
申请日:
2018.03.29
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018202294A120180426.pdf#####ABSTRACT A trifunctional molecule comprising a target-specific ligand, a ligand that binds a protein associated with the TCR complex and a T cell receptor signaling 5 domain polypeptide is provided. Engineering T cells with this novel receptor engenders antigen specific activation of numerous T cell functions, including cytokine production, degranulation and cytolysis.
