PROBLEM TO BE SOLVED: To provide a pharmaceutical composition capable of suppressing decomposition of a specific quinolinecarboxylic acid compound or a salt thereof, and a production method thereof.SOLUTION: A solid pharmaceutical composition contains a compound represented by the general formula (1) or a salt thereof, a cellulose-based excipient, and an acidic substance having a pH of 4.0 or less. (R1 is a C1 to 3 alkyl group which may be 1 or 2 or more-substituted by H, a halogen atom, an amino group or a cyano group R2 is a C1 to 3 alkyl group, H, a halogen atom, a hydroxyl group or an amino group R3 is H or a halogen atom R4 is H or F and X is a halogen atom.)COPYRIGHT: (C)2015,JPO&INPIT