A detachable prosthodontic device (100) includes an abutment (110), a suprastructure (120), and a dental screw (130). The abutment (110) includes a hollow chamber (112). A screw hole (517) is arranged on an abutment wall (115) of the hollow chamber (112). The suprastructure (120) is provided with a receiving region (121) and an inner surface (122) surrounding the receiving region (121). The dental screw (130) includes a screw head (132) and a screw rod (134). The screw head (132) includes a contact member (222) and a guiding member (224). When the dental screw (130) is mounted in the screw hole (517), a portion of the screw head (132) protrudes outward from an outer surface (114) of the hollow chamber (112). When the suprastructure (120) is sleeved onto the abutment (110), partial area of the outer surface (114) of the hollow chamber (112) contacts with partial area of the inner surface (122) of the suprastructure (120), and the screw head (132) supports an opposing side of the inner surface (122) to apply a force onto the inner surface (122) to thereby retain the suprastructure (120) onto the abutment (110).