Kottayil, S. George,Kumar, Amresh,Sunthankar, Prasanna,Kavuru, Vimal
申请号：
AU2017249396
公开号：
AU2017249396A1
申请日:
2017.04.12
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
A nimodipine injection concentrate and diluted formulation comprises nimodipine (base or salt), an effective amount of a hydrophilic surfactant, and a pharmaceutically acceptable carrier for injection which is an aqueous solution, an organic solvent, an oil, or a cyclodextrin, such that the nimodipine is substantially contained in a concentrated injection solution, suspension, emulsion or complex as a micelle or a colloidal particle or an inclusion complex and the formulation is stable and clear. In certain embodiments, the hydrophilic surfactant is polysorbate 80.
