compounds \u0434\u043b\u0438\u043d\u043d\u043e\u0446\u0435\u043f\u043e\u0447\u0435\u0447\u043d\u044b\u0445 derivatives \u0434\u0438\u043c\u0435\u0442\u0438\u043b\u0430\u043d\u0438\u043b\u0438\u043d\u0430, ways of obtaining them, \u0441\u0430\u043c\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u0443\u044e\u0449\u0438\u0435\u0441\u044f textures, as well as their application
The present invention relates to long-chain dimethylaniline derivative compounds, their preparation methods, self-assembled texture, and uses thereof. Said compounds show ultralong acting anaesthetic effect, and belong to N-diethylaminoacetyl-2,6-dimethylaniline compounds, having a structure according to formula (I). Said compounds may self-assemble into micelle or gel in an aqueous solvent, and exert an in vivo elongated local anesthetic actions. Local anesthesia and/or analgesic activity can last more than 72 hours. The biomaterials can self-assemble into micelles or gels in water and have local anesthetic effect, as well ascanfurther be used as the coating of medicinal bioactive molecules for treatment of pain, itching and the like and/or the drug carriers, together with as pharmaceutical adjuvants for delivery system. Thus, said materials have a favourable perspective.
