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COMPOSITIONS ET PROCEDES POUR LE TRAITEMENT D'AFFECTIONS RETINIENNES DEGENERATIVES
专利权人:
THE PROVOST; FELLOWS; FOUNDATION SCHOLARS; AND THE OTHER MEMBERS OF BOARD; OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
发明人:
CAMPBELL, MATTHEW,HUMPHRIES, PETER,HUMPHRIES, MARIAN,KIANG, ANNA-SOPHIA,DOYLE, SARAH,O'NEILL, LUKE
申请号:
CA2849816
公开号:
CA2849816A1
申请日:
2012.10.01
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention is directed to compositions and methods for the treatment of degenerative retinal conditions. According to a general aspect, the present invention is directed to inflammatory mediators, preferably components or substrates of the NLRP3-inflammasome, for use in the treatment of degenerative retinal conditions involving drusen and anaphylatoxin-induced choroidal- neovascularisation. The invention is also directed to a method for the treatment of degenerative retinal conditions involving drusen and anaphylatoxin-induced choroidal-neovascularisation and to recombinant vectors and recombinant proteins for use in such methods. The present invention also provides a method for determining the risk of developing or monitoring the progression of diseases involving drusen and anaphylatoxin-induced choroidal neo-vascularisation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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