Formulation for administration of RNA

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专利权人:

BioNTech RNA Pharmaceuticals GmbH;TRON - Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gGmbH

发明人:

SAHIN, Ugur,HAAS, Heinrich,VOGEL, Annette,ERBAR, Stephanie,WALZER, Kerstin,SCHLEGEL, Anne,HÖRNER, Sebastian,MORENO HERRERO, Jorge,KLAMP, Thorsten,KREITER, Sebastian,DIKEN, Mustafa

申请号：

AU2019207761

公开号：

AU2019207761A1

申请日:

2019.01.10

申请国别(地区):

AU

年份:

2020

代理人:

摘要：

The present invention relates to compositions comprising polyplex formulations for delivery of RNA to a target organ or a target cell after parenteral administration, in particular after intramuscular administration. More precisely, the present invention relates to formulations for administration of RNA such as self-replicating RNA, in particular by intramuscular injection. In more detail, the formulations comprise polyplex particles from single stranded RNA and a polyalkyleneimine.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/