FORMULATION D'ADMINISTRATION D'ARN.农业专利-农业学术服务平台

专利权人:: BIONTECH RNA PHARMACEUTICALS GMBH;TRON-TRANSLATIONALE ONKOLOGIE AN DER UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ GEMEINNUTZIGE GMBH

发明人:: SAHIN, UGUR,HAAS, HEINRICH,VOGEL, ANNETTE,ERBAR, STEPHANIE,WALZER, KERSTIN,SCHLEGEL, ANNE,HORNER, SEBASTIAN,MORENO HERRERO, JORGE,KLAMP, THORSTEN,KREITER, SEBASTIAN,DIKEN, MUSTAFA,HOERNER, SEBASTIAN

摘要：: The present invention relates to compositions comprising polyplex formulations for delivery of RNA to a target organ or a target cell after parenteral administration, in particular after intramuscular administration. More precisely, the present invention relates to formulations for administration of RNA such as self-replicating RNA, in particular by intramuscular injection. In more detail, the formulations comprise polyplex particles from single stranded RNA and a polyalkyleneimine.