Use of a combination of at least two active ingredients comprising (i) an extract of lotus, (ii) an extract of pomegranate ( Punica granatum) and (iii) a methylxanthine comprising caffeine, theophylline, theobromine or paraxanthine, or plant extract rich in methylxanthines, as agent for preventing or reducing the signs of aging of the skin or hair, is claimed. ACTIVITY : Dermatological； Endocrine-Gen. MECHANISM OF ACTION : 5' Adenosine monophosphate activated protein kinase activator.
