The invention relates to the use of a combination of at least two active principles chosen from (i) a lotus extract, (ii) a pomegranate (Punica granatum) extract and (iii) a xanthine base chosen from caffeine, theophylline, theobromine and paraxanthine, or a plant extract rich in xanthine base, as slimming agent. It also relates to a cosmetic treatment method for preventing or reducing the increase in the volume of adipose tissue and/or the formation of fatty lumps.