REY, DIEGO, ARIEL,DEFOREST, NIKOL,COX, HEATHER,SHUKLA, SONI
申请号:
SG11201507463W
公开号:
SG11201507463WA
申请日:
2014.03.13
申请国别(地区):
SG
年份:
2015
代理人:
摘要:
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non-replicative transduction particles as reporter molecules.