Rey, Diego Ariel,Deforest, Nikol,Cox, Heather,Shukla, Soni
申请号：
AU2014243796
公开号：
AU2014243796A1
申请日:
2014.03.13
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems. The reporter nucleic acid molecules include a reporter gene, such as a reporter molecule or selectable marker, for detecting target genes or cells. Methods and systems are provided for detection of cells and target nucleic acid molecules using the non- replicative transduction particles as reporter molecules.
