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EXOSOME PACKAGING OF NUCLEIC ACIDS
专利权人:
发明人:
申请号:
EP16849987.9
公开号:
EP3356519A1
申请日:
2016.09.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A method for preparing exosomes or exosome-like vesicles packaged with a nucleic acid of interest is provided. In certain embodiments, the method may comprise: introducing into an exosome-producing cell a nucleic acid construct comprising the nucleic acid sequence of interest incorporated in a pre-miR-451 structural mimic, and allowing the cell to produce exosomes. Nucleic acid constructs, compositions, and uses thereof are also provided.
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