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METHOD FOR INDUCING T CELLS FOR CELL-BASED IMMUNOTHERAPY
专利权人:
Hiroshi KAWAMOTO
发明人:
Hiroshi Kawamoto,Kyoko Masuda,Takuya Maeda,Seiji Nagano,Yoshimoto Katsura
申请号:
US15326940
公开号:
US20170296649A1
申请日:
2015.07.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided is a method for inducing T cells for a cell-based immunotherapy, which comprises the steps of: (1) providing human pluripotent stem cells bearing a T cell receptor specific for a desired antigen, and (2) inducing T cell progenitors or mature T cells from the pluripotent stem cells of step (1). Especially, a method for inducing T cells for a cell-based immunotherapy from cells of a person who is not the subject to be treated by the cell-based immunotherapy. The method provided herein may further comprise a step of co-culturing the T cell progenitors or mature T cells induced from the pluripotent stem cells with the lymphocytes of the subject to be treated by the cell based immunotherapy to verify that the T cells are not allogenicaly reactive against the subject.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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