Use of (N- [2, 4 -bis (1, 1 -dimethylethyl) - 5 - hydroxyphenyl] - 1, 4 - dihydro - 4 - oxoquinoline - 3 - ca rboxamide) for treating CFTR mediated diseases

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专利权人:

Vertex Pharmaceuticals Incorporated

发明人:

Van Goor, Fredrick F.,Burton, William Lawrence,Huang, Chien-Jung,Negulescu, Paul Adrian,Yu, Haihui

申请号：

AU2012332225

公开号：

AU2012332225A1

申请日:

2012.11.02

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention relates to the use of N-[2,4-bis(l,l-dimethylethyl)-5- hydroxyphenyl]-l,4-dihydro-4-oxoquinoline-3-carboxamide, solids forms, and pharmaceutical compositions thereof for the treatment of CFTR mediated diseases, particularly cystic fibrosis, in patients possessing specific genetic mutations.

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中国工程科技知识中心

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