Paul McCray,Shyam Ramachandran,Yi Xing,Michael Welsh,Mark Behlke
申请号：
US14376810
公开号：
US20150045410A1
申请日:
2013.02.06
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to therapeutic agents comprising miR-138, a miR-138 mimic, a SIN3A RNAi molecule, or a an anti-SIN3A RNAi molecule, and/or an anti-SIN3A antisense oligonucleotide (ASO) or other agent that suppresses SIN3A expression, a small molecule drug that interferes with SIN3A activity or whose actions mimic the biological effects of SIN3A suppression and methods of use of these therapeutic agents to treat cystic fibrosis.
