McCray, Paul,Ramachandran, Shyam,Xing, Yi,Welsh, Michael,Behlke, Mark
申请号：
AU2013217105
公开号：
AU2013217105A1
申请日:
2013.02.06
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to therapeutic agents comprising miR-138, a miR-138 mimic, a SIN3A RNAi molecule, or a an anti-SIN3A RNAi molecule, and/or an anti-SIN3A antisense oligonucleotide (ASO) or other agent that suppresses SIN3A expression, a small molecule drug that interferes with SIN3A activity or whose actions mimic the biological effects of SIN3A suppression and methods of use of these therapeutic agents to treat cystic fibrosis.
