SPECK, GEORG,EICKMEIER, CHRISTIAN,PESTEL, SABINE,GERMEYER, SABINE,PIEPER, MICHAEL P.,BREITFELDER, STEFFEN,GRAUERT, MATTHIAS
申请号：
CA2474874
公开号：
CA2474874C
申请日:
2003.01.21
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to novel anticholinergics of general formula 1(see formula 1)in which X- denotes an anion with a single negative charge； A and B which maybe identical or different denote -O-, -S-, -NH-, -CH2-, -CH=CH- or -N(C1-C4alkyl)-；R denotes hydrogen, hydroxy, halogen, optionally substituted alkyl oralkylene,optionally substituted alkoxy or -O-alkylene, or optionally substituted-O-C(O)-alkyl or alkylene； R1 and R2 which may be identical or differentdenoteoptionally substituted alkyl or together, denote an alkylene bridge； R3, R4,R3', R4',R x and R x' which may be identical or different, denote hydrogen, optionallysubstituted alkyl, alkoxy, hydroxy, cyano, nitro or halogen； or R x and R x'togetherdenote a bond or bridging group, processes for preparing them and their use aspharmaceutical compositions.
