ORBITAL ATK, INC.; INC.;ORBITAL ATK;EPICENTRX, INC.
发明人:
KNOX, SUSAN,CANNIZZO, LOUIS,WARNER, KIRSTIN,WARDLE, ROBERT,VELARDE, STEPHEN,NING, SHOUCHENG,BEDNARSKI, MARK D.
申请号：
ES06801575
公开号：
ES2532457T3
申请日:
2006.08.14
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
A compound of Structural Formula (I): ** Formula ** or salts, solvates or hydrates thereof in which: R1, R2, R3 and R4 are each independently, hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heteroalkyl, substituted heteroalkyl, heteroarylalkyl, substituted heteroarylalkyl, halo, hydroxy or nitro； R5 and R6 are each independently, hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl, heteroaryl, substituted heteroaryl, heteroalkyl, substituted heteroalkyl, heteroarylalkyl, substituted heteroarylalkyl, halo, hydroxy or nitro； or is 0, 1, 2, 3 or 4； R7 is acyl substituted with one or more of halogen, -CF3 or -OS (O) 2R8； R8 is alkyl, substituted alkyl, aryl or substituted aryl； provided that at least one of R1, R2, R3, R4, R5 and R6 are nitro； wherein, except as already provided for the variable R7, substituted refers to the substituents M, -R60, -O, -OR60, -SR60, -S, -NR60R61, -NR60, -CF3, -CN, -OCN, -SCN, -NO, -NO2, -ONO2, -N2, -N3, -S (O) 2OH, -S (O) 2R60, -OS (O) 2R60, -OP (O) (OR60) (OR61), -C (O) R60, -C (S) R60, -C (O) OR60, -C (O) NR60R61, -C (S) OR60, -NR62C (O) NR60R61, -NR62C (S ) NR60R61, -NR62C (NR63) NR60R61 and -C (NR62) NR60R61 in which M is independently a halogen； R60, R61, R62 and R63 are independently hydrogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, cycloalkyl, substituted cycloalkyl, cycloheteroalkyl, substituted cycloheteroalkyl, aryl, substituted aryl, heteroaryl or substituted heteroaryl, or optionally R60 and R61 together with the atom of nitrogen to which they are attached form a cycloheteroalkyl or substituted cycloheteroalkyl ring.Un compuesto de Fórmula estructural (I):**Fórmula** o sales, solvatos o hidratos de éste en el que: R1, R2, R3 y R4 son cada uno independientemente, hidrógeno, alquilo, alquilo sustituido, arilo, arilo sustituido, arilalquilo, arilalquilo sustituido, heteroarilo, heteroarilo sust
