HAGER, JEFFREY H.,SMITH, NICHOLAS D.,MANEVAL, EDNA CHOW,KAHRAMAN, MEHMET,GOVEK, STEVEN P.
申请号：
PE2015002634
公开号：
PE20160157A1
申请日:
2014.06.18
申请国别(地区):
PE
年份:
2016
代理人:
摘要：
It refers to the compound (± 2 - (4 - (2 - (3 - (fluorescence) azetidin-1-il) etoxi) phenyl-3 - (3-hydroxyphenyl) - 4-methyl-2h-chromium-6-ol, and the counterpart (R) of its preparation (II) and (III), as well as its salts and solutions. These compounds are modulators of estrogen receptor, so they are useful in the treatment of breast cancer, ovarian cancer, uterine cancer, prostate cancer, lung cancer and uterine cancer.SE REFIERE AL COMPUESTO (±)-2-(4-(2-(3-(FLUOROMETIL)AZETIDIN-1-IL)ETOXI)FENIL)-3-(3-HIDROXIFENIL)-4-METIL-2H-CROMEN-6-OL, ASI COMO A SUS ENANTIOMEROS (R) DE FORMULA (II) Y (S) DE FORMULA (III), Y SALES Y SOLVATOS DE LOS MISMOS. DICHOS COMPUESTOS SON MODULADORES DE LOS RECEPTORES DE ESTROGENO, POR LO CUAL SON UTILES EN EL TRATAMIENTO DE CANCER DE MAMA, CANCER DE OVARIO, CANCER DE ENDOMETRIO, CANCER DE PROSTATA, CANCER DE PULMON Y CANCER DE UTERO, ENTRE OTROS
