CANCER RESEARCH TECHNOLOGY LIMITED;THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL
发明人:
BELLENIE, BENJAMIN RICHARD,CHEUNG, KWAI MING JACK,DAVIS, OWEN ALEXANDER,HOELDER, SWEN,HUCKVALE, ROSEMARY,COLLIE, GAVIN,MENICONI, MIRCO,BRENNAN, ALFIE,LLOYD, MATTHEW GARTH
申请号:
CA3095371
公开号:
CA3095371A1
申请日:
2019.04.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to compounds of formula I that function as inhibitors of BCL6 (B-cell lymphoma 6) activity Formula (I) wherein X1, X2, R1, R2, R30, R31 and Ring A are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which BCL6 activity is implicated.