The present invention relates to combinations comprising anti-progastrin (anti-hPG) monoclonal antibodies and immune checkpoint inhibitors, as well as pharmaceutical compositions comprising said combinations. Methods of treatment of cancer using said combinations are also provided.本發明係有關於包含抗前胃泌激素(抗-hPG)單株抗體及免疫查核點抑制劑之組合,以及包含該等組合之藥學組成物。亦提供使用該等組合之癌症治療方法。