The present invention is directed to antibodies against human transforming growth factor beta receptor II (TGFβRII), pharmaceutical compositions comprising antibodies and methods of using the antibodies, alone or in combination, for example, for treating cancer and fibrosis.本發明係關於對抗人類轉化生長因子β受體II(TGFβRII)之抗體,包含該等抗體之醫藥組合物,及單獨或組合使用該等抗體於例如治療癌症及纖維變性之方法。