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Administration of a bispecific construct binding to CD33 and CD3 for use in a method for the treatment of myeloid leukemia
专利权人:
Amgen Research (Munich) GmbH
发明人:
Zugmaier, Gerhard,Kufer, Peter,Kischel, Roman,Subklewe, Marion,Krupka, Christina
申请号:
AU2017253621
公开号:
AU2017253621A1
申请日:
2017.04.18
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention provides a bispecific construct comprising a first binding domain specifically binding to CD33 and a second binding domain specifically binding to CD3 for use in a method for the treatment of myeloid leukemia, wherein the construct is administered for a maximal period of 14 days followed by a period of at least 14 days without administration of the construct. Moreover, the invention provides a method for the treatment of myeloid leukemia comprising the administration of a therapeutically efficientamount of such bispecific construct and the use of such bispecific construct for the preparation of a pharmaceutical composition for the treatment of myeloid leukemia.
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中国工程科技知识中心
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