The present invention is directed towards a lyophilized or reconstituted multi-antigen or multicomponent immunogenic composition comprising antigens from a staphylococcal bacterium. The antigens, which are polypeptides and polysaccharides, may be obtained, inter alia, directly from the bacterium using isolation procedures, or they may be produced using synthetic protocols, or they may be recombinantly produced using genetic engineering procedures, or through a combination of any of the foregoing.본 발명은 스타필로코커스 세균으로부터 단리된 1종 이상의 항원을 포함하는 동결건조된 또는 재구성된 다중항원 또는 다중성분 면역원성 조성물, 및 이를 제조하는 방법에 관한 것이다.