COMPOSE DE CYCLOPROPYLAMINE FLUOREE, PROCEDE DE PREPARATION DE CE DERNIER, COMPOSITION PHARMACEUTIQUE BASEE SUR CE DERNIER, ET UTILISATIONS DE CE DERNIER

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专利权人:

CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA

发明人:

LIU, HONG,LI, JIA,WANG, JIANG,SU, MINGBO,WANG, SHUNI,ZHOU, YUBO,ZHU, WEI,XU, WEI,LI, CHUNPU,JIANG, HUALIANG,CHEN, KAIXIAN

申请号：

CA3021608

公开号：

CA3021608A1

申请日:

2017.03.16

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Provided are a compound represented by formula I, a raceme thereof, an R-isomer thereof, an S-isomer thereof, a pharmaceutical salt thereof, and a mixture thereof, a preparation method therefor, a pharmaceutical composition comprising the compound, and uses thereof serving as an lysine specific demethylase 1 (LSD1) inhibitor. Provided are uses of the fluorinated cyclopropylamine compound represented by formula I in the treatment of cancers.

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