FLUORINATED CYCLOPROPYLAMINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USES THEREOF

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专利权人:

CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA

发明人:

Hong LIU,Jia LI,Jiang WANG,Mingbo SU,Shuni WANG,Yubo ZHOU,Wei ZHU,Wei XU,Chunpu LI,Hualiang JIANG,Kaixian CHEN

申请号：

US16085311

公开号：

US20190100507A1

申请日:

2017.03.16

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Provided is a fluorinated cyclopropylamine compound represented by formula I, a racemate thereof, an R-isomer thereof, an S-isomer thereof, a pharmaceutical salt thereof, and a mixture thereof. Also provided are pharmaceutical compositions containing the compound, a preparation method for the compound, and uses thereof as a lysine specific demethylase 1 (LSD1) inhibitor, and in the treatment of cancers.

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中国工程科技知识中心

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http://www.ckcest.cn/home/