FLUORINATED CYCLOPROPYLAMINE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USERS THEREOF

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专利权人:

CHINESE ACADEMY OF SCIENCES;SHANGHAI INSTITUTE OF MATERIA MEDICA

发明人:

LIU, Hong,LI, Jia,WANG, Jiang,SU, Mingbo,WANG, Shuni,ZHOU, Yubo,ZHU, Wei,XU, Wei,LI, Chunpu,JIANG, Hualiang,CHEN, Kaixian

申请号：

SG11201808017P

公开号：

SG11201808017PA

申请日:

2017.03.16

申请国别(地区):

SG

年份:

2018

代理人:

摘要：

Provided are a compound represented by formula I, a raceme thereof, an R-isomer thereof, an S-isomer thereof, a pharmaceutical salt thereof, and a mixture thereof, a preparation method therefor, a pharmaceutical composition comprising the compound, and uses thereof serving as an lysine specific demethylase 1 (LSD1) inhibitor. Provided are uses of the fluorinated cyclopropylamine compound represented by formula I in the treatment of cancers.

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http://www.ckcest.cn/home/