NEW MDR1 INHIBITORS FOR OVERCOMING MULTIDRUG RESISTANCE

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专利权人:

发明人:

申请号：

EP15756848.6

公开号：

EP3193858A1

申请日:

2015.08.03

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

New inhibitors of the activity of the multidrug resistance receptor 1 (MDR1), which are highly active to the MDR1 transporter, and showing a medium/ high selectivity to such transporter, described by the structural formula (I): where R is a C1-C4 alkylene, optionally substituted with a C1-C3 alkyl. Said inhibitors are useful in the treatment or prevention of multi-drug resistance.

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