Provided herein is a method for producing a tablet comprising ibuprofen, which is simple and inexpensive compared with that of the prior art. A tablet comprising ibuprofen is made by compressing an ibuprofen powder or ibuprofen containing particles as tablet powders, wherein more than 70 wt% of said ibuprofen powders are composed of ibuprofen particles having 75~1000 &mgr;m in diameter. Also provided herein is a method for producing a tablet comprising ibuprofen, which is characterized by compressed molding of tablet powders, wherein said tablet powders are made by adjusting ibuprofen powders or ibuprofen containing particles so that more than 70 wt% of said ibuprofen powders are composed of ibuprofen particles having 75~1,000 &mgr;m in diameter.提供一種比習知技術更為便宜、簡便之含有異布洛芬的藥片之製造方法。;一種含有異布洛芬的藥片,係將70質量%以上之粒子之粒徑為75微米~1000微米之異布洛芬(ibuprofen)原料粉末或是含有異布洛芬之顆粒作為壓片粉末,進行壓縮成型而得到之含有異布洛芬之藥片;以及一種含有異布洛芬的藥片之製造方法,其特徵為,將異布洛芬原料粉末或含有異布洛芬之顆粒調整為其70質量%以上之粒子之粒徑為75微米~1000微米後,將其作為壓片粉末而進行壓縮成型。