Disclosed is an effervescent ibuprofen formulation comprising (a) an active ingredient-containing granule which comprises ibuprofen and a basic excipient, and (b) an effervescent granule which comprises an acid component e.g. malic, ascorbic or citric acid and a carbon dioxide-forming component e.g., hydrogen carbonate salts wherein the active ingredient-containing granule comprises the ibuprofen in the form of a water-soluble salt, and wherein the formulation is produced by a process in which the active ingredient-containing granule is prepared by intensively mixing ibuprofen in the form of its free acid with one or more basic excipients without adding water.
