The United States of America, as represented by the Secretary, Department of Health and Human Services;SRI International
发明人:
Irving W. Wainer,Michel Bernier,Lawrence Robert Toll,Lucita Arenas Jimenez
申请号：
US15273147
公开号：
US10130594B2
申请日:
2016.09.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogs for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analog or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
