Irving W. Wainer,Michel Bernier,Lawrence Robert Toll,Lucita Arenas Jimenez
申请号：
US13583206
公开号：
US20130005799A1
申请日:
2011.03.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This disclosure concerns the discovery of the use of fenoterol and (R,R)- and (R,S)-fenoterol analogues for the treatment of a tumor expressing a β2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a β2-adrenergic receptor. In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject.
