COMPOUND OR PHARMACEUTICALLY ACCEPTABLE DERIVATIVE OF THE SAME, PHARMACEUTICAL COMPOSITION, METHODS FOR INHIBITING AN ACTION OF A SERINE HYDROLASE AND FOR TREATMENT OF A DISEASE MEDIATED BY SERINA HYDROLASE, AND ARTICLE OF MANUFACTURING
KEVIN SHREDER,YI HU,ALLISTER FRASER,YASUSHI KOHNO,AKIHIKO KOJIMA,JUNICHI ISHIYAMA
申请号：
BRPI0716897
公开号：
BRPI0716897A2
申请日:
2007.09.20
申请国别(地区):
BR
年份:
2013
代理人:
摘要：
Provided herein are benzoxazinone compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated diseases.
