PERUMAL, OMATHANU P.,PODARALLA, SATHEESH K.,KAUSHIK, RADHEY S.
申请号:
CA2723563
公开号:
CA2723563C
申请日:
2009.05.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Methods are described for producing non-immunogenicnanoparticles from protein sources by controlling the pH in ananoprecipitationprocess. The nanoparticles that are produced by the disclosed methodsrange in diameter size from about 100 ran to about 400 nm, with apreferred diameter size of from approximately 100 nm to approximately300 nm, thereby rendering them non- immunogenic. The invention furtherdiscloses methods for producing nanoconjugates that are suitable for avariety of therapeutic, diagnostic and other uses.