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Method of Forming Non-Immunogenic Hydrophobic Protein Nanoparticles, and Uses Therefor
专利权人:
South Dakota State University
发明人:
Omathanu P. Perumal,Satheesh K. Podaralla,Radhey S Kaushik
申请号:
US14203476
公开号:
US20140308351A1
申请日:
2014.03.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to approximately 300 nm, thereby rendering them non-immunogenic. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses.
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