SOUTH DAKOTA STATE UNIVERSITY;SATHEESH K. PODARALLA;RADHEY S. KAUSHIK;OMATHANU P. PERUMAL
发明人:
OMATHANU P. PERUMAL,SATHEESH K. PODARALLA,RADHEY S. KAUSHIK
申请号:
IL20915510
公开号:
IL209155A
申请日:
2010.11.04
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
Methods are described for producing non-immunogenic nanoparticles from protein sources by controlling the pH in a nanoprecipitation process. The nanoparticles that are produced by the disclosed methods range in diameter size from about 100 ran to about 400 nm, with a preferred diameter size of from approximately 100 nm to approximately 300 nm, thereby rendering them non-immunogenic. The invention further discloses methods for producing nanoconjugates that are suitable for a variety of therapeutic, diagnostic and other uses.